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Automated High-Volume Analysis For In-Vitro Diagnostics

Simagis Live delivers Automated Virtual Microscopy technology for Biomedical Enterprise of any size. It automates analysis and sharing of large volumes of imaging data for repeatable, routine In-vitro Diagnostics (IVD) tests and has the power to transform  imaging diagnostics with walk-away automation and web-based collaborative work process.

Simagis Live technology automates high volume screening for routine IVD tests that require microscopic evaluation, such as tuberculosis, water and food-borne pathogens, routine pathology tests like "Pap smears" and other common high volume IVD tests. The technology involves rapid automated imaging of the entire microscopy sample slide (Whole Slide Imaging) using a regular commercial microscope, and high-performance analysis of "digital slide" using our proprietary mathematical methods for advanced image analysis.

Using our SIMAGIS® Live Server, users can rapidly acquire, analyze and share a very large number of images in one automated sequence. Our applications can automatically scan full microscope specimen slides, send images to High Performance Server, analyze and publish results for review on a secure web server in a matter of minutes.

SIMAGIS® Live server employs High Performance Computing to handle image arrays of unlimited sizes. Users can review, edit and share results with authorized users via web-based "virtual microscope" interface. As a result, large volumes of images can be analyzed up to 10 times faster with greater accuracy, and experts can review results from anywhere in the world for millions of patients.

Technology can be deployed as SaaS (Software as a Service). Primary applications of technology include microbiology and digital pathology.

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Technology Use Cases Technology Use Cases


Mobile Telemicroscopy

"Better Future" is a global, non-profit health organization fighting Malaria and Tuberculosis in remote areas of Africa, India and Southwest Asia. Microscopy remains primary method of diagnostics for TB and Malaria, and "Better Future" uses portable microscopes developed by scientists in California and Texas to run microcopy blood tests in remote locations. These simple portable microscopes can cost as little as $100, and use cell phone cameras to take the images. An international team of volunteers has trained local staff on collecting and preparing blood samples and taking images, but there are no local experts who can read the images for diagnostics.

"Better Future" is using Simagis Live technology to screen images and send results to experts. Cellular network coverage is making its way to the most remote regions of the world, and cell phone networks are now available in remote town centers. Now local health staff can run microscopy tests in the most remote areas by simply taking images using cell phone camera, and storing them on the cell phone until returning to local town center where network coverage is available. Local staff uses free and friendly Dropbox mobile application to automatically sync up local images with cloud storage whenever cellular data connection is present.

Simagis Live Workspace can "listen" to cloud-based storage locations and process new images as soon as they upload, so the Simagis Live server automatically screens incoming images for signs of malaria and tuberculoses. If disease is detected, the images are immediately shared with expert volunteers worldwide who donate their time to complete the diagnostics. "Better Future" is on a mission to improve global health for the next generation of mankind, using the latest generation of technology.